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NEWS STORY

Numbing the Pain
One of the world's most addictive drugs is staging a dramatic comeback--and nowhere in the country is its use more widespread than in Oregon.

BY CHRIS LYDGATE
clydgate@wweek.com

 

Morphine was first synthesized by German apothecary F.W.A. Setürner in 1805, but the drug did not truly come into its own until the advent of the hypodermic needle later in the century.

 

Despite the surge
in morphine use, many experts say too many patients are still in pain. "The biggest problem is that people who need to get pain medication are still not getting it," says Ann Jackson of the Oregon Hospice Association.

 

This week, The Oregonian published a four-part series on pain management.

 

 

Far from the public eye, in medical institutions that most people prefer not to think about, a quiet revolution is taking place. With little publicity, cancer wards, hospices and pain clinics are doling out larger doses of prescription morphine, so much that per capita morphine consumption has tripled since 1995, making Oregon truly a state of tranquility.

Experts say the sharp rise represents a paradigm shift in the treatment of pain, both in terminal illnesses such as cancer and in chronic conditions such as back injury.

"It doesn't surprise me," says Dr. Brett Stacey, director of the Pain Management Center at Oregon Health Sciences University. "There's been a huge educational effort in recent years to say that using opioids for chronic pain is often appropriate."

For the nation as a whole, per-capita morphine consumption has more than doubled over the last four years--from 1,076 grams per 100,000 population in 1995 to a projected 2,636 grams this year, according to the federal Drug Enforcement Agency.

In Oregon, the jump has been even more pronounced, soaring from 1,463 grams four years ago to a projected 4,980 grams in 1999, making us the morphine capital of America.

How did we get here? Researchers point to the protracted fight over doctor-assisted suicide."Physician-assisted suicide has elevated awareness by the medical community that a more aggressive approach needs to be applied in pain management," says Bob Dernedde, executive director of the Oregon Medical Association.

Earlier this month, for example, the Oregon Board of Medical Examiners took unprecedented disciplinary action against Roseburg doctor Paul Bilder for under-prescribing pain medications to patients, several of whom were dying of cancer.

One of the oldest and most powerful drugs known to modern medicine, morphine was first widely used during the Civil War. Ironically, its addictive qualities were poorly understood--doctors hoped that injecting morphine would somehow stave off the habit-forming properties associated with smoking or eating opium--and many soldiers wound up addicted to the drug.

More than a century later, the specter of drug-addicted patients still haunts American medicine. In recent years, doctors have tended to be miserly in prescribing morphine, fearing that their patients would get sucked into the vortex of addiction.

Research now suggests, however, that when properly monitored, the use of morphine to treat severe pain is unlikely to result in addiction, says David Joranson, director of the Pain and Policy Studies Group in Madison, Wis.

Doctors have also worried that a generous prescription pen would invite scrutiny from state and federal investigators charged with combating the drug scourge. "The war on drugs was not just fought in the streets," says Barbara Coombs Lee of the Compassion in Dying Federation. "It was fought at the bedside of dying patients."

Another factor in the surge of morphine use was the passage of Oregon's Intractable Pain Act in 1995, which set out specific guidelines for the prescription of painkillers, freeing physicians from the anxiety that they might be investigated.

The BME's action against Dr. Bilder shows that the grin-and-bear-it philosophy no longer carries the official seal of approval. "The culture has changed," says Dr. Susan Tolle, director of the Center for Ethics in Health Care at OHSU.

Studies demonstrate that morphine and other narcotics are extremely effective in treating the agonizing pain associated with terminal cancer, says Dr. Stacey of OHSU. While there is little research showing the benefits of morphine in the treatment of other kinds of pain, there are no studies showing that it has negative effects, so doctors are increasingly prescribing it in chronic conditions and after major surgery or even childbirth.

"We used to say, 'Of course you're going to hurt the next day,'" says Dr. Tolle. "Now we say, 'What can we do for you?'"


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Willamette Week | originally published September 15, 1999

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